Endocrine Abstracts

Background: Papillary thyroid carcinoma (PTC) is known as the most common histological subtype of thyroid carcinoma. The prognosis of PTC is generally favorable. However, small number of patients with PTC progressed with distant metastasis and invasion to adjacent organs. New diagnostic tool for early detection of PTC with poor outcome is desired. We previously reported that autoantibody to WD repeat domain 1 (AWA) in the serum was associated with the existence of undifferenti...

Background and objective: Sleep disorders (SDs) are classified into subjective and objective SDs, and subjective SDs are directly related to quality of life. According to previous studies, Graves’ disease (GD) causes SDs, especially insomnia. However, the characteristics of subjective SDs and its clinical course after hyperthyroidism normalization remain unclear. Additionally, the factors involved in subjective SDs with hyperthyroidism in GD remain unclear. Hyperthyroidis...

Objective: Osteoporosis and osteopenia (OS/OP) are frequent in patients with cortisol-producing adrenal adenomas (CPA) associated with severity of cortisol excess (CE). However, the relationship between OS/OP and CE severity considering sex differences is unknown.Patients and Methods: This was a retrospective cross-sectional observational study conducted as a part of the Advancing Care and Pathogenesis of Intractable Adrenal Disease in Japan (ACPA-J) stu...